Slc26a7 thyroid

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August undefined, 2024

WebDec 7, 2024 · SLC26A7 is proposed to be an anion transporter in the thyroid gland. The mutation leads to a frameshift and a premature stop codon. The predicted protein is truncated and very likely to be nonfunctional if it was expressed at all. In addition, in silico studies predict the mutation to be pathogenic. Figures References Related Details … WebMay 25, 2024 · In the process of thyroid hormone synthesis, there are four important proteins (sodium iodide transport, NIS; pendrin, PDS; SLC26A7; iodotyrosine deiodinase, …

Regulation of solute carrier family 26 member 7 (Slc26a7) …

WebDec 7, 2024 · SLC26A7 is proposed to be an anion transporter in the thyroid gland. The mutation leads to a frameshift and a premature stop codon. The predicted protein is … WebJan 20, 2024 · The latest research has indicated SLC26A7 functions as a novel iodide transporter in the thyroid; SLC26A7 dysfunction can affect thyroid hormonogenesis and … gospel bluegrass radio stations free

Localisation of SLC26A7. a Immunofluorescence analysis of FLAG …

WebSLC26A7 was first discovered as a chloride/anion exchanger in the kidney and stomach and plays a role in iodine transport and thyroid hormone biosynthesis in thyrocytes. ... WebMar 21, 2024 · SLC26A7 (Solute Carrier Family 26 Member 7) is a Protein Coding gene. Diseases associated with SLC26A7 include Congenital Hypothyroidism and Dyshormonogenic Goiter. Among its related … gospel bridge illustration powerpoint

Regulation of solute carrier family 26 member 7 (Slc26a7) by thyroid …

A Novel Homozygous Mutation in the Solute Carrier Family 26

WebApr 13, 2024 · The mission of the Public Health Genomics is to integrate advances in human genetics into public health research, policy, and programs WebJul 4, 2024 · SLC26A7 was first identified as a chloride anion exchanger in the kidneys and stomach 9. SLC26A7 dysfunction was initially thought to cause renal tubular acidosis and … chief frame machine clampsWebJul 24, 2024 · SLC26A7 is expressed in thyroid tissues We first conducted an immunohistochemical analysis to confirm SLC26A7 expression in human thyroid tissues. SLC26A7 signals were detected predominantly on the apical side facing the follicular lumen in thyroid follicular cells (Fig. 1a, Supplementary Fig. 1 ). chief frame machine repair in ri

"WebJun 8, 2024 · SLC26A6 (also known as putative anion transporter 1 [PAT1]) is a Cl – /HCO 3 – exchanger expressed at the luminal membrane of enterocytes where it facilitates intestinal Cl – and fluid absorption. Here, high-throughput screening of 50,000 synthetic small molecules in cells expressing PAT1 and a halide-sensing fluorescent protein identified … " - Slc26a7 thyroid

Slc26a7 thyroid

Molecular Analysis of Congenital Hypothyroidism in Saudi Arabia:

Web500 bp SLC26A7 200 bp GAPDH Merge Thyroid-4 Thyroid-5 Thyroid-7 Thyroid-10 Kidney-1 Kidney-2 Kidney-3 Kidney-4 Liver SLC5A5 DAPI SLC26A4 SLC5A5 DAPI Fig. 1 Expression of SLC26A7 in thyroid tissues ... WebJul 24, 2024 · Here, we show that SLC26A7 is a novel iodide transporter in the thyroid. We observe that SLC26A7 is specifically expressed in normal thyroid tissues and …

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WebHuman pathology. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. SLC26A7. WebExpression of SLC26A7 (SUT2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... THYROID CANCER - Interactive survival scatter plot i & Survival analysis i. SLC26A7 is not prognostic in thyroid cancer ...

WebJul 4, 2024 · Slc26a7-/-mice showed goitrous congenital hypothyroidism and mild growth failure on a normal diet. Slc26a7 -/- mice with a low iodine environment showed marked … WebThyroid carcinoma. Uterine Carcinosarcoma. Uterine Corpus Endometrial Carcinoma. Uveal Melanoma. SLC26A7 expression based on . Comparison: Statistical significance: Normal-vs-Primary: 1.62447832963153E-12: Pan-cancer view Methylation Survival Correlated genes ...

WebA Novel Homozygous Mutation in the Solute Carrier Family 26 Member 7 Gene Causes Thyroid Dyshormonogenesis in a Girl with Congenital Hypothyroidism A Novel Homozygous Mutation in the Solute Carrier Family 26 Member 7 Gene Causes Thyroid Dyshormonogenesis in a Girl with Congenital Hypothyroidism Thyroid. 2024 Jul 16. doi: … WebLe portail des maladies rares et des médicaments orphelins. Diagnose van hypoplasie van schildklier (gen panel) Diagnosis of thyroid hypoplasia (gene panel)

WebApr 12, 2024 · SLC26A7 Antibody (14H5) is a mouse monoclonal IgG 2a κ SLC26A7 antibody, cited in 3 publications, provided at 200 µg/ml. raised against the hydrophilic C …

WebMar 31, 2024 · The functional analysis indicated that these genes were significantly enriched in diverse biological processes (BP) and pathways related to the malignancy processes. Four of these genes (RDH5, TREM1, BIRC7, and SLC26A7) were selected to construct the risk evaluation model. chief four seasWebOct 18, 2024 · Here, we report homozygous truncating mutations in SLC26A7 in 6 unrelated families with goitrous CH and show that goitrous hypothyroidism also occurs in Slc26a7-null mice. In both species, the gene is expressed predominantly in the thyroid gland, and loss of function is associated with impaired availability of iodine for thyroid hormone ... gospel brunch near meWebSep 23, 2024 · SLC26A7, a member of the SLC26 gene family of anion channels and exchangers, has been shown to be expressed in a limited number of tissues including stomach , kidney (12, 27, 37), inner ear , and thyroid , where it has been proposed to function as a Cl − / HCO 3 − exchanger or an anion channel that transports Cl − or I − . gospel brunch halls chophouseWebThe main function of the thyroid gland is the regulation of metabolic rate. It produces the thyroid hormones thyroxine (T4) and triiodothyronine (T3), which increase heart rate, respiration and gastrointestinal motility and stimulate carbohydrate and fat metabolism. ... SLC26A7: solute carrier family 26 member 7: Detected in some: 330.3: 14 ... chief frame machines for saleWebOct 18, 2024 · SLC26A7 is a member of the same transporter family as SLC26A4 (pendrin), an anion exchanger with affinity for iodide and chloride (among others), whose gene … chief frame machine pricesWebIn addition, follicular Tg inhibited the ability of TSH to induce the membrane localization of SLC26A7. In rat thyroid sections, the expression of SLC26A7 was weaker in follicles with a higher ... gospel books in the bibleWebOct 18, 2024 · SLC26A7 is a member of the same transporter family as SLC26A4 (pendrin), an anion exchanger with affinity for iodide and chloride (among others), whose gene mutations cause congenital deafness and dyshormonogenic goiter. However, in contrast to pendrin, SLC26A7 does not mediate cellular iodide efflux and hearing in affected … gospel brunch in nyc