Phospho s727
WebJan 11, 2012 · It has been shown that Ser727 of STAT3 is phosphorylated by various kinases, including mitogen-activated kinases (MAPK), H7-sensitive kinase, protein kinase Cδ, cyclin-dependent kinase 5 (CDK5), the mammalian target of rapamycin kinase (mTOR), nemo-like kinase (NLK), death-associated protein kinase 3 (DAPK3), and mitogen- and … WebProduct Name Phospho-STAT3(S727) Rabbit mAb; Host Species Rabbit ; Clonality Monoclonal ; Clone No. SY24-09; Purification ProA affinity purified; Applications WB, …
Phospho s727
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WebThe STAT3 Phospho (Ser727) antibody recognizes the regulatory serine phosphorylation of human STAT3 protein. RRID AB_2734543 (BioLegend Cat. No. 698911) AB_2734544 (BioLegend Cat. No. 698912) Antigen Details Structure STAT3 is a … WebThe first USS Sappho (ID-1427) was a United States Navy ferry transport in commission from 1918 to 1919. Sappho was built in 1886 as a wooden - hulled commercial ferry …
WebPhospho S727 (2) Phospho S51 (1) Asymmetric DiMethyl R3 (1) MonoMethyl R26 (1) Phospho S380 (1) Symmetric DiMethyl R2 (1) Phospho S33 (1) Acetyl K23 (1) Asymmetric DiMethyl R8 (1) DiMethyl K14 (1) MonoMethyl R17 (1) MonoMethyl R8 (1) MonoMethyl R3 (1) Phospho S455 (1) Phospho Thr4 (1) Phospho S259 (1) Phospho S957 (1) Phospho … WebHSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway (2,3). Phosphorylation of HSP27 causes a …
WebProperties. Description. Rabbit Monoclonal Antibody to STAT3 (phospho S727) Background. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. WebHere, we studied the role of STAT3 activation on tyrosine 705 (Y705) and serine 727 (S727) in glioma radioresistance. This study explored STAT3 phosphorylation on Y705 (pSTAT3-Y705) and S727 (pSTAT3-S727) in glioma cell lines and in clinical samples. Radiosensitizing effect of STAT3 activation down-modulation by Gö6976 was explored.
WebHuman Phospho-STAT3 (S727) Antibody Summary Species Reactivity Human Specificity Detects human STAT3 when phosphorylated at S727 in Western blots. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human STAT3 S727 site Accession # P40763 Formulation
WebOct 30, 2006 · In vivo analyses of S727 of Stat1 and Stat3 using knock-in mouse models showed that S727 plays important physiological roles [13], [14]. However, the biochemical function underlying the physiological importance of the phospho-serine and conserved LPMSP motif is not completely understood. greenlight trading chicagoWebFeb 5, 2024 · TGFβ is the prototype of a large family of pluripotent cytokines with diverse effects on cellular proliferation, tumor growth, apoptosis, differentiation, fibrosis, anti-inflammation, and embryo development [1,2,3,4,5].The competence of TGFβ cytokine signaling plays an important role in determining lineage acquisition in cells of … flyingfalcon.orgWebNov 13, 2024 · Phospho-S727 Stat3 localizes in mitochondria. Recently, Larner and Levy groups described that phospho-Stat3 S727, but not phospho-Stat3 Y705, led to the … greenlight toys trucksWebStat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor comp greenlight toy police carsWebJan 15, 2001 · S727 phosphorylation of STAT1 in interferon-γ (IFN-γ)-treated mouse fibroblasts occurred without a need for p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinases 1 and 2 or c-Jun kinases, and required both an intact SH2 domain and phosphorylation of Y701. flying familyWebSynthetic peptide within Human STAT1 (phospho S727). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Database link: P42224 greenlight toys trucks and trailersWebPhospho-Stat3 (Ser727) Antibody recognizes endogenous levels of Stat3 only when phosphorylated at Ser727. The antibody does not significantly cross-react with the … greenlight toy trailer