WebThe first efficient intermolecular addition of nitroalkanes to activated enynes for asymmetric synthesis of 2,3-allenoates is described. It is a new addition to the limited available strategies for catalytic asymmetric synthesis of allenoates. Enabled by a new bifunctional catalyst, a range of trisubstituted allenoates can be obtained in excellent chemical and … Web1 jan. 1989 · Activation of 2-alkyn-1-ols as their methanesulfonate esters and displacement with hydrazine furnishes the corresponding alkynyl hydrazine derivatives which undergo smooth oxidative rearrangement with diethyl azodicarboxylate (DEAD) or 4-methyl-1,2,4-triazoline-3,5-dione (MTAD) to form allenes.
Andrew G. Myers - Publications
Web5 jan. 2024 · in organic synthesis [45,46], the rearrangement of 2 to 1 (Scheme2) has the potential to be a valuable, complementary tool, in the synthesis of 1,3-dienes. The focus of this review will therefore be the rearrangement of allenes not predisposed to rearrangement through direct attachment of heteroatoms or electron-withdrawing groups (e.g., 3e). WebHugelshofer CL, Mellem KT, Myers AG. Synthesis of quaternary α-methyl α-amino acids by asymmetric alkylation of pseudoephenamine alaninamide pivaldimine. Organic Letters. 15: 3134-7. PMID 23746325 DOI: ... Allene synthesis from 2-alkyn-1-ols Tetrahedron Letters. 30: 5747-5750. DOI: 10.1016/S0040-4039(00)76187-9 : 0.709: 1988: patate rosse usi
A Surprising Switch from the Myers–Saito Cyclization to a Novel ...
Web8 mei 1996 · An efficient nickel-catalyzed asymmetric propargylic substitution reaction/Myers rearrangement of racemic propargYlic carbonates that furnishes a series … Web29 jun. 2024 · Radical synthesis of allenes from 1,3-enynes. 1,3-Enynes are common and useful building blocks in organic synthesis. For examples, with the assistance of organometallic reagents, the groups of Ma, 7 Kambe, 8 Yoshida, 9 and Kimura 10 have built elegant methods for the synthesis of allenes through nucleophilic 1,4 … Web27 mrt. 2024 · The Blaise-Maire reaction is the Blaise ketone synthesis using β-hydroxy acid chlorides to give β-hydroxyketones, which are converted into α,β-unsaturated ketones using sulfuric acid. Ketone Formation from Organocadmium Compounds. This ketone formation is an identical reaction to the Blaise ketone synthesis. patate ruggiero