WebNational Center for Biotechnology Information Web30 ott 2007 · Abstract. Cardiac sarcoplasmic reticulum (SR) Ca 2+ ATPase (SERCA2a) plays a central role in myocardial contractility. SERCA2a actively transports Ca 2+ into the SR and regulates cytosolic Ca 2+ concentration, SR Ca 2+ load, and the rate of contraction and relaxation of the heart. In the heart, SERCA pump activity is regulated by two small …
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WebPotent and selective irreversible gastric H + /K + ATPase pump inhibitor. CAS Number: 117976-90-6. Purity: > 98%. Soluble in water to 25 mM and in ethanol to 75 mM. Form / State: Solid. Source: Synthetic. Web1 feb 2002 · Using an antiserum to the alpha subunit of the pig H + /K +-ATPase pump, ... (HCl) by parietal cells involves translocation of HK-ATPase-containing cytoplasmic tubulovesicles to the apical ... food foundry bury
The renal H+-K+-ATPases: physiology, regulation, and …
Web20 ore fa · The pump is a two-state system, with states ‘f’ and ‘e’ characterized by the presence and absence of ions. The pump makes random transitions between these two … Web20 ore fa · Working mechanism of an active ion transport pump and Na-K exchange rate affected by the intracellular ADP or extracellular Na concentration. a Catalytic cycle of P-type ATPases exemplified by a ... Web24 mar 2024 · How does HK ATPase pump work? The gastric H,K-ATPase of the parietal cell pumps acid, which is the final step of gastric acid secretion in the stomach. Stimulation of the parietal cell moves the H,K-ATPase into the secretory canaliculi, and the enzyme then can pump acid by becoming associated with K+ and Cl− conductance. elddis approved workshop