WebFeb 16, 2024 · patients receiving high-dose cyclophosphamide (2.5> g), the incidence of hyponatremia (defined as serum sodium <135mEq/L) was 52%, with 8.9% having symptomatic hyponatremia.22 Onset has been described in 4–12h of cyclophosphamide administration and usually resolves within 24–48 h. 7 Again, SIADH has been implicated as WebHyponatremia is an electrolyte imbalance and is indicated by a low level of sodium in the blood. The normal adult value for sodium is 136-145 mEq/L. Sodium is an element, or an electrolyte, that is found in the blood. ... Heparin, certain chemotherapy drugs (Aminoglutethimide, Cyclophosphamide and Vincristine). Conditions related to steroid ...
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WebHyponatremia is found among people who take Cytoxan, especially for people who are female, 50-59 old, have been taking the drug for < 1 month. The phase IV clinical … WebMay 17, 2024 · Seek emergency care for anyone who develops severe signs and symptoms of hyponatremia, such as nausea and vomiting, confusion, seizures, or lost … green promoting
Cytoxan and Hyponatremia - a phase IV clinical study of FDA data
WebAug 19, 2024 · Cytoxan (cyclophosphamide) is a cancer ( chemotherapy) medication used to treat several types of cancer. Cytoxan is also used to treat certain cases of nephrotic syndrome (kidney disease) in children. What are side effects of Cytoxan? Common side effects of Cytoxan include: nausea or vomiting (may be severe), loss of … WebJul 2, 2024 · CyBorD was given weekly for 6 cycles. Patients had a median of 2 involved organs (kidney, 68%; cardiac, 61%). Patients received a median of 16 (range, 1-23) treatment cycles. Treatment-emergent adverse events were consistent with DARA SC in MM and CyBorD. Infusion-related reactions occurred in 1 patient (grade 1). WebThe exact mechanism of cyclophosphamide-induced hyponatremia is poorly understood, but is thought to occur from a drug- associated antidiuretic hormone (ADH) release leading to free water retention. 1 … green promotion